Glossary

Glossary of BMT and Related Terms

Below is a short list of basic terms and acronyms about BMT, along with references to more comprehensive resources.
Allogeneic: transplant using cells from another person who is not the patient’s twin
ABMDR: American Bone Marrow Donor Registry
ACOR: Association of Cancer Online Resources
Antigen: a substance, usually a protein, that causes the body to produce antibodies
Autologous: “self” transplant using one’s own cells
BMDW: Bone Marrow Donors Worldwide
BMT: blood and marrow transplant; bone marrow transplant
CHRMC: Children’s Hospital and Regional Medical Center
CB or UCB: cord blood, umbilical cord blood
Conditioning: high-dose chemotherapy and/or radiation administered to rid the patient of their diseased immune system immediately prior to HCT
CRIR: Caitlin Raymond International Registry
DNA: deoxyribonucleic acid, a substance found in the cells of all living things, which carries the genetic code for that organism, which determines its function, growth, and features, such as color of eyes, hair, skin, etc.
Donor: the person whose blood-forming cells are transplanted into the patient
FHCRC: Fred Hutchinson Cancer Research Center
GVHD: Graft Versus Host Disease
Haplotype: a group of human leukocyte antigens
Hematological: “of the blood”; a hematologist is a physician who treats diseases of the blood
Hematopoietic: “blood forming”
HCT: hematopoietic cell transplant, refers to all types of cell sources
HLA: Human Leukocyte Antigen, refers to proteins located at certain sites (on chromosome 6) on the surface of white blood cells that control the body’s immune response, determining if a rejection reaction will occur between cells of the immune system of 2 people, i.e., between donor and recipient
HLA typing: (also called tissue typing) testing of DNA to determine similarity or difference, and the degree thereof, between the HLA antigens of a patient and of a potential donor
MUD: Matched Unrelated Donor, now commonly called URD
NMDP: National Marrow Donor Program
OPA: Office of Patient Advocacy of the NMDP
PBSCT: peripheral blood stem cell transplant
Recipient: the patient who receives the transplant
SCCA: Seattle Cancer Care Alliance, formed of FHCRC, CHRMC, and UWMC
SCT: stem cell transplant
Stem cells: blood-forming cells found in bone marrow, peripheral blood, and umbilical cord blood; not to be confused with embryonic stem cells
Syngeneic: refers to transplant from an identical twin donor
Tissue typing: same as HLA typing
URD: Unrelated Donor, same as MUD
UWMC: University of Washington Medical Center
WMDA: World Marrow Donor Association

BMT Glossary Resources

National Marrow Donor Program Glossary
Mayo Clinic Glossary of Terms Related to Bone Marrow Transplant
UCSF Pediatric Bone Marrow Transplant Program: Glossary

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